It is possible depending on the type. Answer a few questions though.
1. Do you have the material properties specified in the model?
2. Are you trying to perform a stress analysis/FEA or a dynamic simulation?
3. Is the model you have shown a part file or assembly file?
If it is in fact a stress analysis/FEA, I have a tutorial written up on my profile which could help you get started on learning how to do one in Inventor.